Lesion-Specific Metabolic Alterations in Relapsing-Remitting Multiple Sclerosis Via 7 T Magnetic Resonance Spectroscopic Imaging.

Alexandra Lipka,Eva Niess,Assunta Dal-Bianco,Gilbert J Hangel,Paulus S Rommer,Bernhard Strasser,Stanislav Motyka,Lukas Hingerl,Thomas Berger,Petra Hnilicová,Ema Kantorová,Fritz Leutmezer,Egon Kurča,Stephan Gruber,Siegfried Trattnig,Wolfgang Bogner

Investigative radiology（2023）

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摘要

7 T MRSI allows in vivo visualization of focal MS pathology not visible on cMRI and the assessment of metabolite levels in the lesion center, in the active lesion periphery and in cortical lesions. This demonstrated the potential of MRSI to image mIns as an early biomarker in lesion development.

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关键词

magnetic resonance spectroscopic imaging,multiple sclerosis,demyelination,lesion,metabolic,7 T

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