UBE3D Is Involved in Blue Light-Induced Retinal Damage by Regulating Double-Strand Break Repair.
Investigative ophthalmology & visual science(2022)
Abstract
Hence, we propose that one potential mechanism that UBE3D-V379M contributes to AMD pathogenesis might be via defective DNA damage repair linked with oxidative stress and our results offered a potential direction for the treatment of AMD.
MoreTranslated text
Key words
age-related macular degeneration (AMD), double-strand break repair (DSBR), KAP1, heterochromatin, methionine oxidation, ubiquitin-protein ligase E3D (UBE3D)
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined