Box-Behnken响应面分析法优化芎麻滴丸的制备工艺
RENSHEN YANJIU(2022)
Abstract
目的 优化芎麻滴丸的制备工艺.方法 以基质与药物配比、药液温度、滴速为考察因素,采用Box-Behnken响应面分析法优化芎麻滴丸的制备工艺.结果 芎麻滴丸的最佳成型工艺中基质与药物比为4:6:1、药液温度为90℃、滴速为30 d/min.结论 经优化后的芎麻滴丸大小、颜色均匀且无粘连、拖尾.因此,优化后的芎麻滴丸制备工艺稳定可行.
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