Arctigenin attenuates paraquat-induced human lung epithelial A549 cell injury by suppressing ROS/p38 mitogen-activated protein kinases-mediated apoptosis.

Chao Liu,Zhao-rui Sun,Meng-meng Wang,Zhi-zhou Yang,Wei Zhang,Yi Ren,Xiao-qin Han,Rui Liu,Quan Li,Shi-nan Nie

World journal of emergency medicine（2022）

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摘要

Arctigenin could attenuate PQ-induced lung epithelial A549 cell injury in vitro by suppressing ROS/p38 MAPK-mediated cell apoptosis, and arctigenin might be considered a potential candidate drug for PQ-induced ALI.

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关键词

A549 cells,Apoptosis,Arctigenin,Mitogen-activated protein kinases,Paraquat,Reactive oxygen species

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