Intermediate-Term Outcomes Following Transcatheter Aortic Valve Implantation in Patients with a History of Chest Radiation Therapy: A Propensity Score Matched Analysis

Chest radiation therapy (XRT) has been associated with a higher rate of mortality following surgical aortic valve replacement. We performed a single -center retrospective analysis of patients with severe AS who underwent TAVI from 01/01/2012 to 07/31/2020 comparing patients with and without XRT. A total of 915 patients met inclusion criteria, with a total of fifty patients found to have a history of XRT. At a mean follow-up of 2.4 years, unadjusted and propensity score matching analysis demonstrated no differences in mortality, heart failure or bleeding -related hospitalization, overall stroke and 30 -day pacemaker implantation in patients with and without XRT.