3.0 T MRI 3种扫描序列对腰椎小关节软骨成像的对比研究
Chinese Journal of Magnetic Resonance Imaging(2022)
Abstract
目的 比较3种3.0 T MRI扫描序列对腰椎小关节软骨成像的图像质量及特点.材料与方法前瞻性纳入健康受试者30例,均接受L4/L5~L5/S1的3.0 T MRI的腰椎常规序列(T1WI及T2WI序列)、三维快速扰相梯度回波水激励序列(water excitation three-dimensional spoiled gradient echo sequence,3D-WATSc)、基于T1加权的三维快速场回波(three-dimensional T1 fast field echo,3D-T1-FFE)、基于质子密度加权的三维各向同性快速自旋回波(three-dimensional proton density weighted imaging volumetric isotropic turbo spin echo acquisition,3D-PDWI-VISTA)序列扫描.对MRI图像进行成像效果的定性和定量评估.定性评估指标包括软骨的信号均匀性、软骨—关节间隙的边缘清晰度、软骨—骨的边缘锐度、软骨—关节间隙的对比度、软骨—骨的对比度;定量评估指标包括图像信噪比(signal to noise ratio,SNR)和对比噪声比(contrast to noise ratio,CNR).结果 3D-WATSc序列在5项定性评估指标中评分最高,3D-T1-FFE序列次之,仅软骨的信号均匀性指标在二者之间的差异具有统计学意义(P<0.05).3D-PDWI-VISTA序列的5项定性指标评分均最差(P<0.05),且几乎不能分辨小关节的各层解剖结构,无法进行后续定量评估.3D-WATSc序列显示其软骨SNR[L4/L5(70.73±14.86)、L5/S1(73.50±13.63)]及软骨—关节间隙[L4/L5(25.30±8.44)、L5/S1(21.64±13.01)]、软骨—骨[L4/L5(60.75±14.68)、L5/S1(64.31±12.98)]、软骨—骨髓的CNR[L4/L5(50.22±14.33)、L5/S1(54.46±10.99)]均较3D-T1-FFE序列高,且差异具有统计学意义(P<0.05).结论 3.0 T MRI的3D-WATSc序列能够清晰地呈现腰椎小关节的软骨层及关节间隙,优于3D-T1-FFE及3D-PDWI-VISTA序列,对腰椎小关节软骨成像及腰椎小关节退变的临床诊断更具优势.
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