The regulation of proliferation and apoptosis in hepatocellular carcinoma via insulin-like growth factor 1 receptor

Guanjun Xu, Jiesheng Chu, Yu Shi,Longzhang Huang, Jingzhong Fu

Growth Hormone & IGF Research(2022)

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Abstract
•To explore the effect of IGF-1R on hepatocellular carcinoma cells.•IGF-1R plays an important role in the progression of HCC.•IGF-1R is a potential target for the treatment of HCC in clinic.
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Key words
IGF-1R,BMP-2,BMP-7,Hepatocellular carcinoma,PI3K,AKT
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