Fluorescent indicators for imaging membrane potential of organelles
CURRENT OPINION IN CHEMICAL BIOLOGY(2022)
摘要
Plasma membrane potential is a key driver of the physiology of excitable cells like neurons and cardiomyocytes. Voltage -sensitive fluorescent indicators offer a powerful complement to traditional electrode-based approaches to measuring and monitoring membrane potential. Intracellular organelles can also generate membrane potential, yet the electrode-and fluorescent indicator-based approaches used for plasma membrane potential imaging are difficult to implement on intact organelles in their native environment. Here, we survey recent advances in developing and deploying voltage-sensitive fluo-rescent indicators to interrogate organelle membrane potential in intact cells.
更多查看译文
关键词
Physiology,Membrane potential,Fluorescent dyes,Organelles
AI 理解论文
溯源树
样例
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要