New data analysis for BioSAXS at the ESRF

JOURNAL OF SYNCHROTRON RADIATION(2022)

引用 9|浏览13
暂无评分
摘要
The second phase of the ESRF upgrade program did not only provide a new storage ring (Extremely Brilliant Source, EBS) but also allowed several beamlines to be refurbished. The BioSAXS beamline (located on port BM29) was upgraded with a new wiggler source and a larger detector. All analysis software has been rewritten to cope with the increased data flux and continues to provide beamline users with reduced and pre-processed data in real time. This article describes FreeSAS, an open-source collection of various small-angle scattering analysis algorithms needed to reduce and analyze BioSAXS data, and Dahu, the tool used to interface data analysis with beamline control. It further presents the data-processing pipelines for the different data acquisitions modes of the beamline, using either a sample changer for individual homogeneous samples or an inline size-exclusion chromatography setup.
更多
查看译文
关键词
BioSAXS, online data analysis, solution scattering, proteins, biological small-angle X-ray scattering, automation, high brilliance, structural biology, high-throughput SAXS, size-exclusion chromatography, online purification
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要