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[Bioinformatic analysis of differentially expressed proteins in the dorsal raphe nucleus of rats after continuous treatment with olanzapine].

P Huang, J Zhu, H Li,Y Wang,Y Tang, Q Liu

Nan fang yi ke da xue xue bao = Journal of Southern Medical University（2022）

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Abstract
In the early stage of treatment, olanzapine may contribute to the occurrence of metabolic disorders in rats by regulating the expressions of Cav1, Hsp90b1, Canx, Gnai1, MAPK9, LOC685513 (Gng14) and 5-HTR2 synapse-related proteins in the dorsal raphe nucleus.
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Key words
bioinformatics,dorsal raphe nucleus,iTRAQ technology,metabolic disorders,olanzapine,serotonergic synapse pathway
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