Upregulation of FosB/ΔFosB in limbic circuits after tooth exodontia-induced occlusal instability in an experimental model of unpredictable chronic stress
Brain Research Bulletin(2021)
摘要
•Diazepam prevents FosB/ΔFosB+ upregulation in the limbic areas after exodontia and UCS.•Occlusion dental alteration increases intranuclear neuron activation in CeA, PVN and dPAG regions.•Occlusion alteration model by unilateral exodontia promotes anxiety-like behavior similarly to UCS.
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关键词
EPM,BSA,CFA,CeA,CRH,DAB,dPAG,Dzp,Exo,GABA,HPA,NAc,OF,PAG,PVN,TMD,UCS
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