Single domain antibodies targeting pathological tau protein: Influence of four IgG subclasses on efficacy and toxicity

Erin E. Congdon,Ruimin Pan,Yixiang Jiang,Leslie A. Sandusky-Beltran, Andie Dodge,Yan Lin,Mengyu Liu,Min-Hao Kuo,Xiang-Peng Kong,Einar M. Sigurdsson

eBioMedicine（2022）

引用 4|浏览9

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摘要

Funding for these studies was provided by the National Institute of Health (R01 AG032611, R01 NS077239, RF1 NS120488, R21 AG 069475, R21 AG 058282, T32AG052909), and the NYU Alzheimer's Disease Center Pilot Grant Program (via P30 AG008051).

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关键词

Tau,Immunotherapy,Antibody subclass,Single domain antibody,Microdialysis,Primary culture,PHF

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