Risk of adverse events with liraglutide in heart failure with reduced ejection fraction: A post hoc analysis of the FIGHT trial.
Diabetes, obesity & metabolism(2023)
摘要
In patients with HFrEF, liraglutide might increase the risk of cardiovascular adverse effects, an effect possibly driven by excess risk of arrhythmias and worsening HF events. As this was a post hoc analysis, these results should be interpreted as exploratory and hypothesis-generating. Further RCTs must be conducted before drawing definitive conclusions.
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关键词
GLP-1 receptor agonists,adverse events,arrhythmia,heart failure hospitalizations,heart failure with reduced ejection fraction,liraglutide
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