Autophagy inhibition restores CD200 expression under IL-1β microenvironment in placental mesenchymal stem cells of fetal origin and improves its pulmonary fibrosis therapeutic potential

•IL-1βinhibits the expression of CD200 in fPMSCs.•IL-1βrestricts immunosuppressive function of fPMSCs for macrophage activation.•Autophgy induced by IL-1βdetermined CD200 expression level.•IL-1βinduces autophagy via activation of p38 signaling.•Inhibiting autophagy enhance therapeutic efficacy of fPMSCs for PF.