EP08.02-070 High Incidence of Peridiagnosis Thromboembolic Events In Patients with BRAF Mutant Lung Cancer

I. Aparicio Salcedo,P. Iranzo Gómez,R. Reyes,H. Bote de Cabo,M. Saigi Morgui,M. Bringas Beranek, J. Bosch-Barrera,J. Corral Jaime,F. Aparisi Aparisi,J.C. Ruffinelli Rodríguez,B. Jiménez Munarríz,Y. Lage Alfranca, R. Lopez-Castro,M. Majem Tarruella,S. Vázquez Estevez,Á. Artal Cortés, Á.R. Rodríguez-Pérez,M. Lázaro Quintela, J.M. Sánchez Torres,N. Reguart Aransay, M. Cucurull Salamero,I. Gil-Bazo,C. Camps Herrero, E. Nadal Alforja,A. del Barrio Díaz Aldagalan,P. Garrido López,M. Dómine Gómez,R. Álvarez Álvarez,A.J. Muñoz Martín,A. Calles Blanco

Journal of Thoracic Oncology（2022）

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摘要

A higher risk of thromboembolic events (TEE) has been recently reported in patients (pts) with non-small-cell lung cancer (NSCLC) harboring ALK or ROS1 gene rearrangements (incidence rate 20-30%). BRAF mutations have been described in 4% of NSCLC. Whether pts with BRAF mutant NSCLC show higher risk of TEE is unknown. We aimed to describe the incidence, characteristics and time of onset of TEE in pts with advanced BRAF mutant NSCLC.

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关键词

braf mutant lung cancer,peridiagnosis thromboembolic events,lung cancer

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