Quality of life of patients with mycosis fungoides and Sezary syndrome

Mycosis fungoides as the most common type and Sezary syndrome as a leukemic variant belong to the rare group of cutaneous T-cell lymphomas. Both diseases are considered incurable and show a chronic course. Since there is no curative treatment, maintaining quality of life and relief of symptoms should be important elements when treating patients with mycosis fungoides and Sezary syndrome. Pruritus, which is a common and burdensome symptom of cutaneous T-cell lymphoma, may negatively impact quality of life. Pruritus and quality of life can be assessed with established measurement tools. Consistent recording enables physicians to recognize restrictions in physical and psychosocial aspects of quality of life early so that therapy can be adapted.