Temporal trajectory model for dopaminergic input to the striatal subregions in Parkinson's disease
Parkinsonism & Related Disorders（2022）
摘要
•Establish a striatal subregional temporal trajectory model and a 4D-temporal trajectory model.•Loss of striatal dopaminergic input first appeared at 14.4 years before the onset.•Trajectory model correlated with the motor severity.
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关键词
Parkinson's disease,Dopamine transporter,Positron emission tomography,Trajectory
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