Pea and Lentil 7s Globulin Crystal Structures with Comparative Immunoglobulin Epitope Mapping

Kelly A. Robinson,Antony D. St-Jacques, Isabella D. Bakestani, Benjamin A. G. Beavington,Michele C. Loewen

SSRN Electronic Journal（2022）

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摘要

•Legumes represent an affordable high protein, nutrient dense food source.•Legume crops contain 7S globulin seed storage proteins that are known allergens.•Crystal structures of pea and lentil 7S globulins are reported for the first time.•3D Ig epitope mapping revealed potential new and differential epitopes.•Prediction of seed storage Ig epitopes enables food security and human health.

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关键词

Pea,Lentil,Food allergen,X-ray crystallography,Immunoglobulin epitope,7S globulin

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