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A subgroup analysis of the ODYSSEY APPRISE study: Safety and efficacy of alirocumab in the Italian cohort

Angelo B. Cefalù, Raffaella Garbelotto,Giuliana Mombelli,Matteo Pirro,Paolo Rubba,Marcello Arca,Claudio Borghi,Katia Bonomo,Stefano Gonnelli, Katia Massaroni, Giampaolo Tirone,Maurizio Averna

Nutrition, Metabolism and Cardiovascular Diseases（2022）

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Abstract
•ODYSSEY APPRISE assessed efficacy and safety of alirocumab in a real-life setting.•255 Italian hypercholesterolemic, high CV risk patients were enrolled in the trial.•Efficacy and safety of alirocumab were comparable in the Italian cohort.•Alirocumab is a beneficial way to further reduce LDL-C in patients at high CV risk.
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Key words
Heterozygous familial hypercholesterolemia,High cardiovascular risk,Alirocumab,LDL-C,Italy
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