Dendritic cells drive profibrotic inflammation and aberrant T cell polarization in systemic sclerosis.
Rheumatology (Oxford, England)（2023）
摘要
Our findings suggest that functional alterations of DCs promote immune mechanisms favouring the aberrant T cell polarization and profibrotic inflammation behind clinical SSc heterogeneity.
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关键词
IL-33,SSc,Th17,dendritic cells,toll-like receptors
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