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Predicting lymphoma in Sjögren's syndrome and the pathogenetic role of parotid microenvironment through precise parotid swelling recording.

Salvatore De Vita,Miriam Isola,Chiara Baldini,Andreas V Goules,Loukas G Chatzis,Luca Quartuccio,Alen Zabotti,Ivan Giovannini,Valentina Donati,Francesco Ferro,Maria Teresa Rizzo,Valeria Manfrè,Enrico Pegolo,Michael Voulgarelis,Francesco Zaja,Renato Fanin,Christos Masaoutis,Dimitra Rontogianni,Dimitrios I Fotiadis,Maurilio Ponzoni,Athanasios G Tzioufas

Rheumatology (Oxford, England)（2023）

Cited 4|Views64
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Abstract
A more precise clinical recording of PSW can improve lymphoma prediction in pSS. PSW as a very early symptom is a predictor, and a longer duration of PSW is associated with a higher risk of NHL. Since lymphoma usually localizes in the parotid glands, and not in the other salivary or lachrymal glands, the parotid microenvironment appears to be involved in the whole history of pSS and related lymphomagenesis.
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Key words
Lymphoma,Parotid,Salivary swelling,Sjögren Syndrome
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