Application of electrochemical biosensor based on metal organic framework materials in cancer detection

In recent years, there has been an increasing study of metal-organic frameworks (MOFs) materials because of their many excellent properties, such as stable skeleton structure, adjustable pore scale, and large specific surface area, which make MOFs a substrate for fixing bioprobes for building electrochemical biosensors. The electrochemical biosensor is a detection device that combines the high specificity of tumor markers with the high sensitivity of electrochemical sensors through sensitive elements, which has a major application in clinical cancer screening. This article provides an overview of the classification of metal-organic skeleton composites, summarizing the various markers (such as cancer markers, microRNAs, and DNA) used over the past five years to detect and predict their development as indicators of early cancer diagnosis.