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PD-L1 and MCL-1 markers and the relationship with prognostic characteristics of differentiated thyroid carcinoma

Endocrine Abstracts(2022)

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Abstract
PDL-1, marker of progression of tumor cells and MCL-1, anti-apoptotic marker, were associated with PTC carrying BRAFV600E mutation, while PDL-1 was associated with more aggressive PTC subtype. MCL-1 and PD-L1 could be useful in composing a panel to assess the prognosis of PTC patients. On the other hand, both markers seemed to have lower relevance to FTC patients.
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Key words
MCL-1,PD-L1,Thyroid carcinoma,Tumor markers
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