Changes in the proteome and secretome of rat liver sinusoidal endothelial cells during early primary culture and effects of dexamethasone.

Ruomei Li,Sabin Bhandari,Inigo Martinez-Zubiaurre,Jack-Ansgar Bruun,Ilona Urbarova,Bård Smedsrød,Jaione Simón-Santamaría,Karen Kristine Sørensen

PloS one（2022）

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摘要

Rat LSECs become activated towards a pro-inflammatory phenotype during early culture. Dexamethasone represses LSEC activation, inhibits apoptosis, and improves cell viability.

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关键词

endothelial cells,rat liver sinusoidal,rat liver,secretome,proteome

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