Astragaloside IV Protects Sepsis-induced Acute Kidney Injury by Attenuating Mitochondrial Dysfunction and Apoptosis in Renal Tubular Epithelial Cells.
Current pharmaceutical design（2022）
Abstract
These studies demonstrated that AS-IV protects against sepsis-induced kidney tubular injury by alleviating oxidative stress, mitochondrial dysfunction possibly associated with the restored cleaved caspase3 pathway.
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Key words
Astragaloside IV,acute kidney injury,cleaved caspase-3,mitochondrial dysfunction,oxidative stress,sepsis
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