WDR5 drives the development of cervical squamous cell carcinoma by inducing epithelial-mesenchymal transition and cancer-associated fibroblasts formation
Pathology - Research and Practice(2022)
Abstract
WDR5 plays a key role in CSCC progression by inducing CXCL8 expression and promoting the transformation of CAFs from epithelial cells.
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Key words
Cervical squamous cell carcinoma,WD repeat domain 5,C-X-C motif chemokine ligand 8,Epithelial-mesenchymal transition,Cancer-associated fibroblasts
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