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PGRS domain structures: Doomed to sail the mycomembrane.

Rita Berisio,Giovanni Delogu

PLoS pathogens（2022）

Cited 5|Views10
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Abstract
The impact of artificial intelligence (AI) in understanding biological processes is potentially immense. Structural elucidation of mycobacterial PE_PGRS is sustenance to unveil the role of these enigmatic proteins. We propose a PGRS "sailing" model as a smart tool to diffuse along the mycomembrane, to expose structural motifs for host interactions, and/or to ship functional protein modules at their C-terminus.
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domain,structures
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