Synthesis of Selenyl-Substituted Quinoline Derivatives via Substrate-Controlled Three-Component Domino Reactions
The Journal of Organic Chemistry(2022)
摘要
A simple and efficient method for the preparation of selenyl-substituted quinoline derivatives through a CSp3–H selenylation of in situ-generated 3-acetyl quinoline has been developed. This protocol is easy to handle, scalable, and good functional group tolerant, providing a rapid method to 3-selenoacetyl quinoline and 3-diselenoacetyl quinoline derivatives.
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关键词
synthesis,reactions,selenyl-substituted,substrate-controlled,three-component
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