Topical Ripasudil for the Treatment of Primary Corneal Endothelial Degeneration in Dogs.

Sarah R Michalak,Soohyun Kim,Sangwan Park,M Isabel Casanova,Morgan A W Bowman,Michelle Ferneding,Brian C Leonard,Kathryn L Good,Jennifer Y Li,Sara M Thomasy

Translational vision science & technology（2022）

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摘要

Topical ripasudil offered a therapeutic benefit in a subset of patients using a canine model of endothelial degeneration, which may guide future trials in humans.

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关键词

canine, corneal endothelium, Fuchs endothelial corneal dystrophy (FECD), Rho associated kinase inhibitor (ROCK), ripasudil

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