Genetic Pathways Underlying Individual Differences in Regular Physical Activity.

Exercise and sport sciences reviews(2023)

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摘要
Twin and family studies show a strong contribution of genetic factors to physical activity (PA) assessed by either self-report or accelerometers. PA heritability is around 43% across the lifespan. Genome-wide association studies have implied biological pathways related to exercise ability and enjoyment. A polygenic score based on genetic variants influencing PA could help improve the success of intervention programs.
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关键词
twin studies,family studies,heritability,genome-wide association,exercise behavior
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