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Palladin promotes cancer stem cell‐like properties in lung cancer by activating Wnt/ Β‐Catenin signaling

Xiong Shu,Meng Chen,Shi‐Ya Liu,Long Yu,Li‐Xin Sun,Li‐Chao Sun,Yu‐Liang Ran

Cancer Medicine（2022）

Cited 1|Views28
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Abstract
Palladin might act as an oncogene by promoting CSCs-like properties and tumorigenicity of NSCLC cells via the Wnt/β-catenin signaling pathway. Besides, Palladin was identified to have the potential as a cell surface marker for LCSCs identification. These findings provide a possible target for developing putative agents targeted to LCSCs.
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Key words
PALLD,Palladin,Wnt/β-catenin signaling,cancer stem cells,lung cancer,stemness
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