Hypoxia and low temperature upregulate transferrin to induce hypercoagulability at high altitude

Meiquan Li,Xiaopeng Tang,Zhiyi Liao,Chuanbin Shen,Ruomei Cheng,Mingqian Fang,Gan Wang,Ya Li, Shuzhen Tang,Li Xie,Zhiye Zhang,Peter Muiruri Kamau,James Mwangi,Qiumin Lu,Yaxiong Li,Yuming Wang,Daniel Thomas MacKeigan,Eric G. Cerenzia,Heyu Ni,Ren Lai

Blood（2022）

引用 13|浏览9

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摘要

•Harmful environmental factors at high altitude upregulate transferrin, which induces hypercoagulability and thromboembolic events.•Transferrin interference may provide a promising strategy for the treatment of high altitude–induced thromboembolic disorders.

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