Small extracellular vesicles from pregnant women with maternal supraphysiological hypercholesterolemia impair endothelial cell function in vitro

Susana Contreras,Rodrigo Escalona,Claudette Cantin,Pascuala Valdivia, David Zapata,Lorena Carvajal,Roberto Brito,Álvaro Cerda,Sebastián Illanes,Jaime Gutiérrez,Andrea Leiva

Atherosclerosis（2023）

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摘要

sEVs from MSPH women impair angiogenesis and nitric oxide synthesis in endothelial cells, which could contribute to MSPH-associated endothelial dysfunction.

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关键词

Angiogenesis,Cholesterol,Endothelial function,Nitric oxide,Pregnancy,Small extracellular vesicles

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