Infants Receiving Very Early Antiretroviral Therapy Have High CD4 Counts in the First Year of Life.

Bryan S Nelson,Camlin Tierney,Deborah Persaud,Jennifer Jao,Mark F Cotton,Yvonne Bryson,Anne Coletti,Theodore D Ruel,Stephen A Spector,Christina Reding, Kira Bacon,Diane Costello,Charlotte Perlowski,Maria Leticia Santos Cruz, Josphat Kosgei,Sai Majji,Dwight E Yin,Patrick Jean-Philippe,Ellen G Chadwick,

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America（2023）

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摘要

We followed 54 infants with in utero HIV after initiating very early antiretroviral treatment. At weeks 24 and 48, ≥80% had CD4 ≥1500 cells/mm3 and CD4% ≥25%. Routine Pneumocystis jirovecii pneumonia prophylaxis in the first year of life may not be necessary for all very early treated infants. CLINICAL TRIALS REGISTRATION:NCT02140255.

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关键词

Pneumocystis jirovecii pneumonia,CD4,HIV,cotrimoxazole,neonatal

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