Detection of emerging neurodegeneration using Bayesian linear mixed-effect modeling

Yann Cobigo,Matthew S Goh,Amy Wolf,Adam M Staffaroni,John Kornak,Bruce L Miller,Gil D Rabinovici,William W Seeley,Salvatore Spina,Adam L Boxer,Bradley F Boeve,Lei Wang,Ricardo Allegri,Marty Farlow,Hiroshi Mori,Richard J Perrin,Joel Kramer, Howard J Rosen

NeuroImage: Clinical（2022）

引用 1|浏览15

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摘要

•Sensitive method for early detection of neurodegenerative cluster trajectories.•Individual Bayesian prediction formalism based on group linear mixed-effect modeling.•Survival analysis showed that the rate of spread is a predictor of time to dementia.

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关键词

Bayesian linear mixed-effect,Bayesian prediction,Alzheimer’s Disease,Frontotemporal Lobar Degeneration

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