Pulmonary Hypertension in Children with Down Syndrome: Results from the Pediatric Pulmonary Hypertension Network Registry

Rachel K Hopper,Steven H Abman,Eleni G Elia,Catherine M Avitabile,Delphine Yung,Mary P Mullen,Eric D Austin,Angela Bates,Stephanie S Handler,Jeffrey A Feinstein,D Dunbar Ivy,John P Kinsella,Kenneth D Mandl,J Usha Raj,Lynn A Sleeper

The Journal of Pediatrics（2023）

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摘要

Despite high rates of cardiac and respiratory comorbidities that influence the severity of pulmonary hypertension, children with Down syndrome-associated pulmonary hypertension generally have a survival rate similar to that of children with non-Down syndrome-associated pulmonary hypertension. Resolution of pulmonary hypertension is common but reduced in children with complicated respiratory comorbidities.

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关键词

Down syndrome,pediatric pulmonary hypertension,pulmonary vascular disease,congenital heart disease,developmental lung disease

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