ASSESSMENT OF RENAL SYMPATHETIC CONTROL USING INVASIVE PRESSURE AND FLOW VELOCITY MEASUREMENTS IN HUMANS.

We show that there are significant variations in the response to sympathetic stimulation following static handgrip exercise using invasive renal arterial measurements. These results demonstrate that intra-arterial renal hemodynamic measurements can be used to determine the renal effect of systemic sympathetic stimulus and allows identification of patients with higher and lower sympathetic control of renal perfusion. This may be useful in determining the response to therapeutic interventions aimed at altering renal sympathetic control.