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Arterial stifness and sympathetic overdrive in hypertensive patients with angina and non-obstructive coronary artery disease

Athanasios Sakalidis,Kyriakos Dimitriadis,Eirini Dri,Stergios Soulaidopoulos,Eleni Manta,Ioannis Leontsinis,Emmanouil Mantzouranis,Christos Fragoulis,Dimitrios Konstantinidis,Konstantinos Tsioufis

JOURNAL OF HYPERTENSION（2022）

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Abstract
Patients with hypertension and non-obstructive CAD are characterized by higher MSNA and increased Aix levels compared to hypertensives without angina and normotensive controls. These preliminary results suggest that therapies targeting sympathetic overdrive and vascular stiffening could provide additional clinical benefit in this special category of hypertensive patients.
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