Triggered Drug Release of Surface Cyclic Peptide Gatekeepers with Endothelial Cell Targeting Sequence Conjugated to Mesoporous Nanocontainers
Materials Letters(2022)
摘要
•The sequence targeting tumor endothelial cell is introduced to the peptide gatekeeper.•The release of entrapped drugs is completely inhibited in the absence of stimuli.•The structure of peptide gatekeeper was converted by addition of bioreductant.•The entrapped drugs in nanocontainers are released on-demand.
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关键词
Stimuli-sensitiveness,Cyclic peptides,Gatekeepers,Mesoporous nanocontainers
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