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Low IGF1 and high IGFBP1 predict diabetes onset in prediabetic patients.

Nina M T Meyer,Stefan Kabisch,Ulrike Dambeck,Caroline Honsek,Margrit Kemper,Christiana Gerbracht,Ayman M Arafat,Andreas L Birkenfeld, Peter E H Schwarz,Jürgen Machann,Martin A Osterhoff,Martin O Weickert,Andreas F H Pfeiffer

European journal of endocrinology（2022）

Cited 4|Views31
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Abstract
Lower IGF1 and higher IGFBP1 in prediabetes predicted the incidence of T2DM, indicating an impairment of beta-cell function, which explains the unresponsiveness to lifestyle intervention.
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Key words
high igfbp1,prediabetic patients,diabetes
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