Genetics of Tremors

Abstract This chapter of the textbook Tremors reviews the contribution of genetics to both isolated tremor, such as essential tremor (ET) and combined tremor syndromes, including tremors syndromes associated with dystonia, Parkinson disease (PD), and ataxia. The chapter builds on the revised criteria for classifying tremor disorders published by the International Parkinson and Movement Disorder Society in 2018. Clinical characteristics of tremor syndromes are used to group the genetic etiologies in order to provide clinicians with a framework to identify possible genetic etiologies in individual patients. The genetics of ET are discussed in detail, with a particular focus on future developments that may finally shed more light on the elusive etiologies of this common disorder.