The different variant allele frequencies of type I/type II mutations and the distinct molecular landscapes in CALR -mutant essential thrombocythaemia and primary myelofibrosis.
Hematology (Amsterdam, Netherlands)(2022)
摘要
The two different subtypes of mutations may have different impacts on MPN. A lower VAF of type I indicates a greater contribution to disease progression in MPN, and increased nondriver mutations may be important in myelofibrosis progression.
更多查看译文
关键词
CALR,essential thrombocythaemia,non-driver mutation,primary myelofibrosis,variant allele frequency
AI 理解论文
溯源树
样例
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要