DFCs/TDM based artificial bio-root to obtain long-term functional root regeneration in non-human primate

Bo Yang,Xueting Yang,Xiangyou Luo,Gang Chen,Jinlong Chen,Fangjun Huo,Zhuoli Zhu,Ye Tian,Weihua Guo,Weidong Tian

Chemical Engineering Journal（2023）

Cited 9|Views24

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Abstract

•A novel functional biological root with a sandwich structure is constructed.•The favorable regeneration potential of FBR is proved in non-human primate over two years of implantation.•The FBR restores the “sandwich” structure of cementum-periodontal ligament-alveolar bone complex.•The FBR exhibits good biocompatibility.

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Key words

Stem cells,Treated dentin matrix,Bio-root,Tooth regeneration,Non-human primates

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