Location Matters: Offset in Tissue Engineered Vascular Graft Implantation Location Affects Wall Shear Stress in Porcine Models

Jacqueline Contento,Paige Mass,Vincent Cleveland,Seda Aslan,Hiroshi Matsushita,Hidenori Hayashi,Vivian Nguyen,Keigo Kawaji,Yue-Hin Loke,Kevin Nelson,Jed Johnson,Axel Krieger,Laura Olivieri,Narutoshi Hibino

JTCVS Open（2022）

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摘要

Patient-specific TEVGs are designed for precise locations to help optimize hemodynamic performance. However, if TEVGs were implanted far from their intended location, worse WSS was observed. This underscores the importance of not only patient-specific design but also precision-guided implantation to optimize hemodynamics in cardiac surgery and increase reproducibility of surgical simulation.

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关键词

tissue-engineered vascular grafts,displacement,wall shear stress,computational fluid dynamics,center of gravity,hemodynamics,surgical planning

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