Urban and rural differences in new onset type 2 diabetes: Comparisons across national and regional samples in the diabetes LEAD network

•Growing evidence suggests that community contextual factors play a critical role in type 2 diabetes (T2D) risk.•Substantial rural and urban disparities in diabetes-related risk factors and outcomes exist in the US.•In three regional and national study samples in the US, we observed differences in T2D risk by community type and region.•These findings suggest that regional and community type-specific risk factors could impact T2D risk.