Copper(i)-catalyzed asymmetric [3 + 2] cycloaddition of N-ester acylhydrazones and β-trifluoromethyl-α,β-unsaturated ketones
Organic Chemistry Frontiers(2022)
摘要
Herein, the first copper(I)-catalyzed asymmetric 1,3-dipolar [3+2] cycloaddition of N-ester acylhydrazones and β-trifluoromethyl-α,β-unsaturated ketones has been developed, affording an array of chiral pyrazolidine derivatives containing a trifluoromethyl moiety bearing vicinal...
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