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解痉多肽表达化生动物模型的研究进展

CHEN Wanqun,ZHANG Jinwei,LUO Yang

Chongqing Medicine（2022）

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Abstract
解痉多肽表达化生(SPEM)为胃癌前病变的初始步骤,动物模型的研究作为探索SPEM及胃癌发生、发展的载体,对胃癌前病变的研究具有价值.目前国内胃癌前病变动物模型研究鲜有涉及SPEM.该文回顾了对于不同药物诱导、幽门螺杆菌(Hp)或猫螺杆菌(H.felis)感染所致的SPEM模型现有研究,以期为研究胃癌前病变提供更多方式和途径.
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