GPR78 Regulates Autophagy and Drug Resistance in Non-small Cell Lung Cancer.

Xuqiang Liao,Renzhong Cai,Gao Li,Fengxia Chen

Alternative therapies in health and medicine（2023）

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Abstract

NSCLC upregulated GPR78. The knockdown of GPR78 can attenuate the proliferation, migration, and invasion of NSCLC cells and increase the apoptosis and autophagy of NSCLC cells that cisplatin has induced. Therefore, targeting GPR78 may be a promising treatment strategy for NSCLC patients.

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Key words

autophagy,lung cancer,gpr78,drug resistance,non-small

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