IL1RAP expression and the enrichment of IL-33 activation signatures in severe neutrophilic asthma.

Yusef Eamon Badi,Barbora Salcman,Adam Taylor,Batika Rana,Nazanin Zounemat Kermani,John H Riley,Sally Worsley,Sharon Mumby,Sven-Eric Dahlen,David Cousins,Silvia Bulfone-Paus,Karen Affleck,Kian Fan Chung,Stewart Bates,Ian M Adcock

Allergy（2023）

引用 9|浏览33

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摘要

IL-33-activated gene signatures are elevated in neutrophilic and mixed granulocytic asthma corresponding with IL1RAP co-receptor expression. This suggests incorporating T2-low asthma in anti-IL-33 trials.

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关键词

IL-33,gene set variation analysis,severe asthma

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