Inflammation in Children with CKD Linked to Gut Dysbiosis and Metabolite Imbalance.
Journal of the American Society of Nephrology : JASN（2022）
摘要
Gut barrier dysfunction and microbial metabolite imbalance apparently mediate the proinflammatory immune phenotype, thereby driving the susceptibility to cardiovascular disease. The data highlight the importance of the microbiota-immune axis in CKD, irrespective of confounding comorbidities.
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关键词
cardiovascular disease,children,chronic inflammation,chronic kidney disease,dysbiosis,hypertension,immunology,pediatric nephrology,vascular disease
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